Search results for "ISM [radio lines]"
showing 10 items of 1018 documents
Effects of sulphonylureas on spontaneous motility and induced contractions in rat isolated uterus
1986
Abstract To clarify the action of sulphonylureas on calcium, the effect of tolbutamide and ghbenclamide has been investigated on a Ca-dependent process, the contractile activity of uterine smooth muscle. Both sulphonylureas antagonized the contractions evoked by CaCl2 in a non-competitive manner when the uterus was maintained in depolarizing solution and did not affect the spontaneous contractions of rat uterus. The capacity of tolbutamide and ghbenclamide to relax vanadate-induced contraction of rat uterus in Ca-free medium suggests that sulphonylureas may have an intracellular site of action related to cytosolic free Ca levels, or effect a reduction in Ca action.
GLP-2 as Beneficial Factor in the Glucose Homeostasis in Mice Fed a High Fat Diet
2015
Glucagon like peptide-2 (GLP-2) is a gastrointestinal hormone released in response to dietary nutrients, which acts through a specific receptor, the GLP-2 receptor (GLP-2R). The physiological effects of GLP-2 are multiple, involving also the intestinal adaptation to high fat diet (HFD). In consideration of the well-known relationship between chronic HFD and impaired glucose metabolism, in the present study we examined if the blocking of the GLP-2 signaling by chronic treatment with the GLP-2R antagonist, GLP-2 (3-33), leads to functional consequences in the regulation of glucose metabolism in HFD-fed mice. Compared with animals fed standard diet (STD), mice at the 10th week of HFD showed hy…
Nowa gospodarka ery informacji
2016
Rewolucyjny rozwój internetu znacząco wpłynął nie tylko na społeczeństwo i kulturę, ale także na gospodarkę. Największe sieciowe korporacje nie pozostały bierne wobec pojawiających się zmian i zaczęły doskonale wykorzystywać ludzkie przywiązanie do sieci. Komercyjny pęd doprowadził wręcz do uprzedmiotowienia człowieka i mierzenia jego wartości w kategoriach ekonomicznych. Kapitalizm odbił swe piętno na funkcjonowaniu sieci, ale sieć, rządząca się swoimi prawami, także zaczęła wpływać na formę tego systemu i ją uaktualniać. Staliśmy się świadkami ewolucji kapitalistycznego rynku i dezaktualizacji niektórych pojęć.
Sexual Dysfunctions and Their Association with the Dual Control Model of Sexual Response in Men and Women with High-Functioning Autism
2019
Adults with an Autism Spectrum Disorder (ASD) are characterized by impairments in social interaction and communication, repetitive and stereotyped interests and behaviours as well as hyper- and/or hyposensitivities. These disorder specific symptoms could be associated with the development of sexual disorders. The Dual Control Model of Sexual Response presents one approach that is frequently used to explain the emergence of sexual dysfunctions. The aim of the present study was to assess the extent of symptoms of sexual dysfunctions in men and women with ASD and to evaluate their association with the individual propensity of sexual excitation and inhibition as defined by the Dual Control Mode…
Representing Tibetan Buddhism in books on spirituality : A discourse-historical approach
2022
This article looks into how Tibetan Buddhism is framed in terms of East-West dichotomy in six popular books on Buddhism and spirituality. Discourse Historical Approach is employed to uncover the rhetorical representation of Tibetan Buddhism to the readers. A critical post-colonial perspective offers an insight into various power dynamics, arising from these representations, structured according to Yoshikawa's model of intercultural communication between East and West. The various power outcomes of rhetorical styles range from Ethnocentric to Dialogical, with their ethical consequences and problematics discussed.
Managerial Capabilities in the Family Tourist Business: Is Professionalization the Key to Their Development?
2021
The main objective of this paper is to analyze the elements of the particular governance structure of the family business and the involvement of the family in the business in order to verify its effects on managerial capabilities. Likewise, professionalization in this type of company will be studied as a moderating variable. To address this analysis, the Resource and Capabilities Based-View and the Agency Theory will be taken as a basis. The empirical study is carried out on a base of 591 Spanish tourism companies using a multiple linear regression analysis. The results show that many of the peculiar characteristics of the family business have a negative effect on their managerial skills, p…
Are fossils enough? Palaeontological tourism based on local dinosaur discoveries
2020
Fossils of dinosaurs and other tetrapods have long aroused interest of scientists and the public opinion alike. Every finding of a new (especially large) species receives coverage in national and international media, and thus, local fossil discoveries might constitute a good basis for local tourism development. The paper aims to examine whether fossiliferous sites on their own may be enough for the development of palaeontological tourism to occur, or do they require the support of additional amusement infrastructure. For this purpose, the interest in chosen localities was analysed using Google and Wikipedia searches, and was further discussed against a survey on dinoparks and their elements…
An interactional ‘live eye tracking’ study in autism spectrum disorder : combining qualitative and quantitative approaches in the study of gaze
2017
Recent studies on gaze behaviours in individuals with autism spectrum disorder (ASD) have utilised “live eye tracking.” Such research has focused on generating quantitative eye tracking measurements, which provide limited (if any) qualitative contextual details of the actual interactions in which gaze occurs. This article presents a novel methodological approach that combines live eye tracking with qualitative interaction analysis, multimodally informed conversation analysis. Drawing on eye tracking and wide-angle video recordings, this combination renders visible some of the functions, or what gaze “does,” in interactional situations. The participants include three children with ASD and th…
What is it and how to measure cultural tourism? A longitudinal study with time series for the Spanish case
2013
Por su poder diferenciador, y su débil contingencia a la moda el turismo cultural se ha convertido en un reto para los destinos. No solo dinamiza zonas de interior sino que es una manera para algunos destinos de salvar su patrimonio y crear empleos. Sin embargo, el concepto de turismo cultural es complejo y su delimitación y medición difíciles. En una primera parte teórica, este trabajo realiza una revisión conceptual del turismo cultural enfocando la dialéctica existente entre experiencia y autenticidad, y destacando después la diversidad de tipologías de turismo y de turista cultural. En la parte empírica, después de abordar la dificultad de medición, se presenta un estudio con series tem…
Chrzest Mieszka w 966 roku. Ewolucja naukowych teorii na podstawie odkryć archeologicznych
2017
Kiedy Mieszko I zanurzył się w wodach chrztu, otworzył potomnym dostęp nie tylko do rodziny królestwa nie z tej ziemi, ale i do rodziny narodów zachodniej kultury. Jego decyzja dała początek państwu polskiemu. Czasowa odległość i skąpy materiał źródłowy sprawiają, że proces poznawczy wciąż jeszcze nie jest zakończony. Autor na podstawie źródeł pisanych ukazuje, w jaki sposób zmieniały się i ewoluowały teorie naukowe dotyczące chrztu Mieszka I. Ich potwierdzenia lub zaprzeczenia szuka opierając się na dokonywanych odkryciach archeologicznych. Po przedstawieniu obrazu państwa Mieszka w 966 r. wskazuje na główne hipotezy dotyczące genezy, czasu i miejsca oraz skutków chrztu władcy. Teorie zmie…